Renee Zellweger 'Happy' People Think She Looks Different

Oscar-winning actress appeared unrecognizable on the red carpet, but she's not the first celeb to dramatically alter her looks.
6:38 | 10/23/14

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Transcript for Renee Zellweger 'Happy' People Think She Looks Different
Did she or didn't she? It's a common question Hollywood stars face along the red carpet, where plastic surgery and speculation about who has done what to their face is rampant. The latest case in point, Renee zellweger, who stopped everyone in their tracks at a benefit this week and came under scrutiny for her altered appearance. Has the quest for perfection gone too far? Here's ABC's Neal Karlinsky. Reporter: When Renee zellweger posed for the paparazzi the other night, heads turned and mouths dropped. The star of "Bridget Jones diary," known for her full cheeks and distinct eyes didn't quite seem to be herself. As in, she looked physically different. Twitter went wild and tabloid headlines online asked, what has Renee zellweger done to her face? On TV, the ladies of "The talk" dug in. I think she's just had the fatty lids removed and I think she looks quite fabulous. However -- at 45, we are used to seeing Renee look a certain way. Reporter: But was it unnatural enhancement or just plain aging? Last night, Renee said, quote, "Perhaps I look different. Who doesn't as they get older? But I am different. I'm happy." For some, the criticism was unfair. At 45, of course she would look different than she did almost 20 years ago in "Jerry Maguire." You had me at hello. Yes, she look drastically different, but you can't blame her for trying to fight the time. Trying to fight age. Reporter: She made no reference to the enhancement rumors, though she did say she is healthy and that her friends say she looks peaceful. Renee said, quote, "For a long time I wasn't doing such a good job with that. I took on a schedule that's not realistically sustainable and didn't allow for taking care of myself. I was aware of the chaos, and finally chose different things." This is really all about the pressure of Hollywood, to stay beautiful. Because when you're beautiful, you're relevant, you get jobs, you get attention. And it's something that all act tregss go through and that trickles down to us regular women, as well. Reporter: Renee aside, many women in Hollywood have admitted trying to reverse the affects of aging and some have regretted it. Courteney cox told "In style" she went overboard with botox in the past and felt trapped in her own skin. Cameron Diaz said she tried botox, too, but told "E.T." Earlier this year she didn't like it. I tried it before, where it's like that little tiny touch of something. It changed my face in such a weird way that I was like, no, I don't -- I don't want to, like, I would rather see myself. I would rather see my face, aging, than a face that doesn't belong to me at all. It would be great to grow old gracefully. If you can have a little help, why not utilize it? Why pick the woman apart for doing what every woman in Hollywood feels they have to do? Reporter: Some women will do just about everything to stop the clock. Women like Janice dick Kinson who I interviewed four years ago. Surgery is good for you. It works for you. Brow lift, yes, I've had my brow lifted. Yes, I had collagen put in. Box toe, plenty. Reporter: You love it. It has to be done. Reporter: Below the next? You want to talk about my breasts? Reporter: Whatever you got. After I had my son, the augmentation pumped up the volume for me. Reporter: But those breast implants were what brought her to the star of the E reality show "Botched." Filled with plastic surgery, allegedly gone wrong. I want to look like a virgin again. This is what happens when they get botched. Reporter:camerins spent more than $12 billion on plastic surgery last year. The doctor says the show captured what they see all the time in their practices. The often hidden but quietly whispered about mistakes. What does it say about society that this show exists right now? When there's plastic surgery, there's surgery. When there's surgery there are complications. Plus, sometimes great isn't good enough. They want perfect. And that pursuit of perfection can sometimes lead to major problems in plastic surgery. Reporter: According to the doctor, breast implants are the most popular, which, as it turns out, they are also the most commonly messed up. And in his experience, in need of fixing. I've seen the entire gamut from too large breast implants that are placed that erode their way through the skin, that when the patient opens their bra, you're looking straight at an implant that has worn a hole. Reporter: You worry that you're seeing so much of this, that people have a problem? I do worry about it. There's patients who have injected themselves with industrial-grade silicone that you see in warehouses. There are people who have gone across the border and had dangerous procedures done for a discount that absolutely turn into a nightmare. Reporter: Janice Dickinson is one of many women who went to the doctor for a tuneup. What bothers you most? My silicone breasts have been in there for about 30 years. Reporter: For her, it wasn't a case of something botched as neglected. The doctor says breast implants need to be replaced every 10 to 15 years. If she has aged, the focus has been on her face. So, any of the surgical procedures she's had on hers have been focused in the upper area. I think she was tired of the paparazzi catching her in photos where she had really bad breasts with lots of rippling and thin skin and it impaired her ability to get certain kinds of jobs. Reporter: She says for 30-year-old implants were having problems and she wanted the doctor to fix them. Though, she didn't seem to want to follow the instructions after surgery. What is that? The drains from my boobs. You took your drain out? Kill me. This is so dangerous, Janice. Oh, my god. Well, I'm sorry. So sue me. She was the most challenging patient I've ever had. Let's put it this way. If I never operate on Janice Dickinson again, that would be too soon. I had eight or nine covers. Reporter: Despite her multiple procedures, Dickinson insists she does not have a problem. Do you think you're addicted to plastic surgery? No. Reporter: You've done a lot. I've done just about as much as every actress and model out there. Reporter: I'm Neal Karlinsky for "Nightline" in Seattle. Up next, just in time for

This transcript has been automatically generated and may not be 100% accurate.

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